Reticulocyte Hemoglobin (Ret-He) Accuracy as A Diagnostic Parameter in Detecting Iron Deficiency Anemia in Children.
DOI:
https://doi.org/10.31004/innovative.v5i4.20842Keywords:
Ret-He,Iron Deficiency Anemia.Abstract
Reticulocyte hemoglobin (Ret-He) is a parameter used to assess the amount of hemoglobin in reticulocyte, thus Ret-He describes the mean of hemoglobin content distribution in the reticulocyte, so that the Ret-He examination can be used as a parameter to diagnose iron deficiency anemia early. Screening of IDA which are cheap and easy is still needed. To analyze whether Ret-He can be a parameter in determining iron deficiency anemia in children. This study is a diagnostic test study. The research data was obtained from outpatient and outpatient laboratory data that showed hypochromic microcytic anemia from July to October 2017 in Department of Pediatrics Moh. Hoesin Hospital Palembang. Data analysis was done using SPSS software. The result of research done by comparison between Ret-He value and transferin saturation value (gold standard). The total number of 120 subjects consisted of 52 subjects in IDA group (TfSat <15%) and 68 subjects in non-IDA group (TfSat ≥15%). The IDA incidence of hypochromic microcytic anemia group in Moh.Hoesin Hospital is 43.3%. The best cut off point of Ret-he is 21.95pg. Based on calculation by using Cut off point 21,95pg, the data obtained NDP 97,8%, NDN 90,5%, RKP 57,6, RKN 0,13 and AUC value 99,8%. Ret- He can be used as a method to detect ID is easy and cheap
References
Badan Penelitian dan Pengembangan Kesehatan. (2013). Riset Kesehatan Dasar (RISKESDAS) 2013. Laporan Nasional 2013. https://doi.org/1 Desember 2013
Bó, S. D., Fragoso, A. L. R., Farias, M. G., Hubner, D. P. G., & de Castro, S. M. (2023). Evaluation of RET-He values as an early indicator of iron deficiency anemia in pregnant women. Hematology, Transfusion and Cell Therapy. https://doi.org/10.1016/j.htct.2021.05.006
Mutalazimah, M., & Putri, D. P. (2021). Helminthiasis, iron intake, and hemoglobin levels in pregnant women. Enfermeria Clinica. https://doi.org/10.1016/j.enfcli.2020.09.011
Mz, M., & Windiastuti, E. (2018). Anemia pada neonatus,Buku ajar hematologi onkologi anak. In Ikatan Dokter Anak Indonesia.
National Institute for Health Research & Development. (2013a). National Health Survey 2013. In Ministry of Health Republic of Indonesia. https://doi.org/10.1007/s13398-014-0173-7.2
National Institute for Health Research & Development. (2013b). Riset Kesehatan Dasar (National Health Survey). Ministry of Health Republic of Indonesia. https://doi.org/10.1007/s13398-014-0173-7.2
Notoatmodjo, S. (2016). Metodologi Penelitian Kesehatan. Jakarta: Rineka Cipta.
Tantawy, A. A., Ragab, I. A., Ismail, E. A., Ebeid, F. S. E., & Al-Bshkar, R. M. (2020). Reticulocyte Hemoglobin Content (Ret He): A Simple Tool for Evaluation of Iron Status in Childhood Cancer. Journal of Pediatric Hematology/Oncology. https://doi.org/10.1097/MPH.0000000000001700
Tiwari, A. K., Bhardwaj, G., Arora, D., Aggarwal, G., Pabbi, S., Dara, R. C., Sachdev, R., Raizada, A., & Sethi, M. (2018). Applying newer parameter Ret-He (reticulocyte haemoglobin equivalent) to assess latent iron deficiency (LID) in blood donors–study at a tertiary care hospital in India. Vox Sanguinis. https://doi.org/10.1111/vox.12700
Wahtini, S. (2019). Faktor-faktor yang berpengaruh dengan kejadian anemia pada bayi. JHeS (Journal of Health Studies). https://doi.org/10.31101/jhes.764
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 Dedianto Dedianto, Dian Puspita Sari, Achirul Bakri, Erial Bahar, Dewi Rosalia Ayu
This work is licensed under a Creative Commons Attribution-ShareAlike 4.0 International License.
