Penjualan Obat Antidiabetes Kombinasi (Jardiance Duo®) Pada Platform  E-Commerce Tokopedia

Ririsiana Nata; Didiek Hardiyanto Soegiantoro; Aloysia Yossy Kurniawati; Ani Kristiyani

doi:10.31004/innovative.v5i3.20011

Authors

Ririsiana Nata Universitas Kristen Immanuel
Didiek Hardiyanto Soegiantoro Universitas Kristen Immanuel
Aloysia Yossy Kurniawati Universitas Kristen Immanuel
Ani Kristiyani Universitas Kristen Immanuel

DOI:

https://doi.org/10.31004/innovative.v5i3.20011

Keywords:

Diabetes Mellitus Type 2, Jardiance Duo, Tokopedia, Selling Price, Selling Region, Sales Volume

Abstract

Type 2 diabetes mellitus (T2DM) is a major health problem in Indonesia with increasing prevalence, driven by lifestyle changes and urbanization. The combination of Metformin and Empagliflozin in the Jardiance Duo® product is one of the effective therapies of choice in managing T2DM. Along with the development of e-commerce in the pharmaceutical sector, the Tokopedia platform has begun to provide access to purchase this drug online. This study aims to analyze the effect of selling price and seller's domicile on the sales volume of Jardiance Duo® on Tokopedia. The problems studied include the extent to which selling price influences purchasing decisions and how the geographic distribution of sellers contributes to sales levels. The study used a quantitative-descriptive approach, with data collected through direct observation on the Tokopedia platform on May 23, 2025. The data studied included price, seller location, and sales volume for each Jardiance Duo® variant. The results showed that the selling price in the range of IDR 443,000–IDR 485,000 had the highest sales volume, reflecting high price sensitivity among consumers. The 12.5/500 mg variant was the best-selling, with the highest sales recorded in West Java and East Java. D.I. Yogyakarta recorded no sales at all, indicating an imbalance in geographical distribution. In addition, the uneven pricing between sellers creates uncertainty for consumers regarding the authenticity of the product. The conclusion of this study emphasizes the importance of a competitive pricing strategy and equitable distribution between regions, as well as the need for price regulation and consumer education to increase trust in online drug purchases. These results are expected to be the basis for consideration for digital pharmaceutical industry players and e-commerce platforms in developing more effective distribution and marketing strategies.

References

Alfian, R., Nita, Y., & Athiyah, U. (2025). Evaluation of Pharmacist-Based Services for Type 2 Diabetes Mellitus in the Indonesian Community Health Centers. Journal of Public Health and Pharmacy, 5(1), 1–10. https://doi.org/10.56338/JPHP.V5I1.5888

Azriful, A., Adnan, Y., Bujawati, E., Alam, S., & Nildawati, N. (2024). Mengungkap Fakta Faktor Risiko Diabetes Melitus Di Indonesia. Media Penelitian Dan Pengembangan Kesehatan, 34(4), 814–823. https://doi.org/10.34011/JMP2K.V34I4.1988

Berends, J., & Gerpott, T. J. (2023). Exploring price tolerance in online retail: A comparative analysis of price comparison website use and repeat purchases. Electronic Commerce Research 2023, 1–21. https://doi.org/10.1007/S10660-023-09791-5

Brewster, S., Holt, R., Portlock, J., & Price, H. (2020). The role of community pharmacists and their position in the delivery of diabetes care: an update for medical professionals. Postgraduate Medical Journal, 96(1138), 473–479. https://doi.org/10.1136/POSTGRADMEDJ-2020-137511

Chen, K., Zha, Y., Alwan, L. C., & Zhang, L. (2020). Dynamic pricing in the presence of reference price effect and consumer strategic behaviour. International Journal of Production Research, 58(2), 546–561. https://doi.org/10.1080/00207543.2019.1598592

Fradesa, F., Abadi, S. P., Maani, B., Hardi, E. A., & Sucipto, S. (2022). Fitur Shopee Barokah dan Tokopedia Salam: Inovasi Marketplace Halal Sebagai Upaya Pengembangan Ekonomi Digital Berbasis Syariah. Jurnal Ilmiah Ekonomi Islam, 8(3), 2893–2902. https://doi.org/10.29040/JIEI.V8I3.6559

Gargya, D., Mirkazemi, C., & Curtain, C. (2022). Qualitative exploration of the experiences of community pharmacists delivering the Diabetes MedsCheck service. Journal of Clinical Pharmacy and Therapeutics, 47(8), 1194–1200. https://doi.org/10.1111/JCPT.13654

Geetha, H., Harigovind PC., & Rakesh PS. (2025). Emerging e-pharmacy sector in India: ethical and regulatory concerns. Indian Journal of Medical Ethics. https://doi.org/10.20529/IJME.2025.041

Goiana-Da-silva, F., Cruz-E-silva, D., Nobre-Da-costa, C., Nunes, A. M., Fialon, M., Egnell, M., Galan, P., Julia, C., Talati, Z., Pettigrew, S., Darzi, A., Araújo, F., & Hercberg, S. (2021). Nutri-Score: The Most Efficient Front-of-Pack Nutrition Label to Inform Portuguese Consumers on the Nutritional Quality of Foods and Help Them Identify Healthier Options in Purchasing Situations. Nutrients 2021, Vol. 13, Page 4335, 13(12), 4335. https://doi.org/10.3390/NU13124335

Grewal, D., Hardesty, D. M., & Iyer, G. R. (2004). The effects of buyer identification and purchase timing on consumers’ perceptions of trust, price fairness, and repurchase intentions. Journal of Interactive Marketing, 18(4), 87–100. https://doi.org/10.1002/DIR.20024

Hartanto, N., Mani, L., Jati, M., Josephine, R., & Hidayat, Z. (2022). Factors Affecting Online Purchase Decision, Customer Satisfaction, and Brand Loyalty: An Empirical Study from Indonesia’s Biggest E-Commerce. Journal of Distribution Science, 20(11), 33–45. https://doi.org/10.15722/JDS.20.11.202211.33

Hogan, M. F., Hackney, D. J., Aplin, A. C., Mundinger, T. O., Larmore, M. J., Castillo, J. J., Esser, N., Zraika, S., & Hull, R. L. (2021). SGLT2-i improves markers of islet endothelial cell function in db/db diabetic mice. Journal of Endocrinology, 248(2), 95–106. https://doi.org/10.1530/JOE-20-0354

Indrahadi, D., Wardana, A., & Pierewan, A. C. (2021). The prevalence of diabetes mellitus and relationship with socioeconomic status in the Indonesian population. Jurnal Gizi Klinik Indonesia, 17(3), 103. https://doi.org/10.22146/IJCN.55003

Langhinrichsen-Rohling, J., Richie, F., Kelley, M., Selwyn, C., Archer, S., & Blejwas, E. (2024). Charitable Pharmacies as Catalysts for Coordinated Care: Pharmacist Management of Blood Glucose Among Under-Resourced Patients With Type 2 Diabetes. Health Promotion Practice, 25(2), 254–262. https://doi.org/10.1177/15248399221115082

Li, S., DeMiguel, V., & Martín-Utrera, A. (2024). Comparing factor models with price-impact costs. Journal of Financial Economics, 162, 103949. https://doi.org/10.1016/J.JFINECO.2024.103949

Lunder, M., Janić, M., Japelj, M., Juretič, A., Janež, A., & Šabovič, M. (2018). Empagliflozin on top of metformin treatment improves arterial function in patients with type 1 diabetes mellitus. Cardiovascular Diabetology, 17(1). https://doi.org/10.1186/S12933-018-0797-6

Madhag, Z., & Al-Isawi, Z. (2024). Empagliflozin alone and in combination with metformin mitigates diabetes-associated renal complications. Journal of Medicine and Life, 17(5), 530. https://doi.org/10.25122/JML-2023-0301

Mannucci, E., & Ghetti, G. (2022). Cost-effectiveness of Empagliflozin, in Addition to Metformin, in Patients with Type 2 Diabetes in Italy. Farmeconomia. Health Economics and Therapeutic Pathways, 23(1). https://doi.org/10.7175/FE.V23I1.1539

Mohaghegh, P., Rezvanfar, M. R., Jalali-Mashayekhi, F., Amerei, Z., & Hosseinzadeh, M. (2023). Comparison of inflammatory markers in type 2 diabetic patients treated with empagliflozin, metformin, and sulfonylurea. Journal of Shahrekord University of Medical Sciences, 25(4), 189–193. https://doi.org/10.34172/JSUMS.794

Nilamsari, W. P., Yusuf, M., Suharjono, Pertiwi, D. A., Dery, A., Suprapti, B., & Zulkarnaen, B. (2020). Study of co-prescription of drugs potentially interacting with warfarin in indonesian ambulatory patients. Research Journal of Pharmacy and Technology, 13(8), 3833–3836. https://doi.org/10.5958/0974-360X.2020.00678.2

Panigoro, E., Harwani, Y., Permana, D., Imaningsih, E. S., & Mahadewi, E. P. (2023). The Impact of Digital Communication on Online Purchasing Behavior among Indonesian Millennials: A Case Study of Tokopedia. JURNAL KOMUNIKASI INDONESIA, 12(2), 8. https://doi.org/10.7454/jkmi.v12i2.1210

Presley, B., Groot, W., Setiawan, E., & Pavlova, M. (2023). Perspectives of pharmacists and patients on pharmacist services to improve medication adherence among patients with diabetes in Indonesia. Journal of Pharmaceutical Health Services Research, 14(2), 167–177. https://doi.org/10.1093/JPHSR/RMAD025

Putra, A. P., Wisandha, I. C., Manalu, J. J., Sugiono, J., Loppies, Y., & Sidik, Y. (2023). Identifying non-adopters’ reason of using e-pharmacy in Indonesia from the benefit and perceived risk. Science Midwifery, 11(1), 92–101. https://doi.org/10.35335/MIDWIFERY.V11I1.1156

Sagita, V. A., Sukmadryani, Y., & Sanjaya, S. (2024). Kajian Artikel: Evaluasi Faktor-Faktor yang Mempengaruhi Waktu Tunggu Pelayanan Resep Rawat Jalan Rumah Sakit di Indonesia Tahun 2023. Barongko: Jurnal Ilmu Kesehatan, 2(3), 498–509. https://doi.org/10.59585/BAJIK.V2I3.438

Sahloul, L., & Salami, M. (2023). A specific new analytical method for determining linagliptin in pure and combination drug products (Empagliflozin and Metformin). https://doi.org/10.21203/RS.3.RS-2880783/V1

Sarkisian, H., Liganenko, M., & Kambiz, S. G. (2022). Modern determinants of consumer needs and analysis of the market of peloidotherapy in SPA resorts. Technology Audit and Production Reserves, 3(4(65)), 32–38. https://doi.org/10.15587/2706-5448.2022.261880

Setiawan, C. D., Wibowo, A., & Athiyah, U. (2023). Regulations of the distribution of pharmaceutical services (pharmacies) locations in Indonesia: A review. Pharmacy Education, 23(4), 274–278. https://doi.org/10.46542/PE.2023.234.274278

Sutanegara, D., Darmono, & Budhiarta, A. A. G. (2000). The epidemiology and management of diabetes mellitus in Indonesia. Diabetes Research and Clinical Practice, 50, S9–S16. https://doi.org/10.1016/S0168-8227(00)00173-X

Tahapary, D. L. (2022). Revisiting metabolic syndrome: The importance of weight management. World Nutrition Journal, 6(S1), 25. https://doi.org/10.25220/WNJ.V06.S1.0017

Tresnadi, S., Linda, M., & Makbul, A. (2025). Tanggung Jawab Hukum Apoteker terhadap Pemberian Obat Keras Tanpa Resep Dokter di Fasilitas Pelayanan Apotek. AKADEMIK: Jurnal Mahasiswa Humanis, 5(1), 169–179. https://doi.org/10.37481/JMH.V5I1.1144

Tuti, D. A., Fitriyani, N. L., & Maulana, J. (2023). Literature Study: Risk Factors for the Incidence of Diabetes Mellitus in Productive Age in Indonesia. Journal of Multidisciplinary Science, 2(6), 288–296. https://doi.org/10.58330/PREVENIRE.V2I6.413

Unade, T. T., & Krishnamanjari Pawar, A. (2022). New Validated Stability-Indicating Rp-HPLC Method for the Simultaneous Determination of Metformin Hydrochloride, Linagliptin and Empagliflozin in Bulk and Pharmaceutical Dosage Forms. International Journal of Applied Pharmaceutics, 14(2), 68–76. https://doi.org/10.22159/IJAP.2022V14I2.43626

Zephaniah, I., & Febrian, D. (2023). Artificial Intelligence to Improve Accuracy and Efficiency of Prescribing Between Doctors & Pharmacists. Metacommunication; Journal of Communication Studies, 8(1), 89. https://doi.org/10.20527/MC.V8I1.15706