Evaluation of Side Effects of Corticosteroid Eye Drops  in Post-Cataract Surgery Patients

Riyadatus Sholihah; M. Shofwan Haris

doi:10.31004/innovative.v5i1.17453

Authors

Riyadatus Sholihah Universitas Ngudia Husada Madura
M. Shofwan Haris Universitas Ngudia Husada Madura

DOI:

https://doi.org/10.31004/innovative.v5i1.17453

Abstract

Corticosteroids are natural steroid hormones in humans produced by the adrenal cortex gland that have a function to treat inflammation or autoimmune disorders in the body. In the case of eye disease, corticosteroid drugs can take the form of eye drops that are widely used in post-cataract surgery patients, which function to reduce inflammation that occurs in the interior segment which sometimes has no apparent cause. The purpose of this study was to determine the side effects that can occur in the use of corticosteroid drugs after cataract surgery. This study was conducted with a crossectional method, which was analysed descriptively using the universal sampling method. This activity uses inclusion and exclusion criteria. The sampling method uses non-random sampling with the time limited sampling method, namely taking all patient's Health Medical Record data. The results and discussion of this study were conducted at the KMU Madura Clinic Pharmacy Installation involving a number of post-cataract surgery patients who used corticosteroid eye drops. The use of corticosteroid eye drops has the potential to cause various side effects. The most common side effects encountered in patients are blurring, stinging, red eyes, and itching. The most widely used eye drops were prednisolone by 53.3%. Based on the above results, it can be described that the length of use of corticosteroid eye drops in patients after cataract surgery at the KMU Madura Eye Clinic pharmacy installation is more than 30 days.

References

Chang DTW, Herceg MC, Bilonick RA, Camejo L, Schuman JS, Noecket RJ. Intracameral dexamethasone reduce inflammation on the first postoperative day after cataract surgery in eyes with and without glaucoma. Clin Ophthalmol.2009;3(1):345-55

Mayangsari E, Lestari B,Soeharto S, Nurdiana, Permatasari N, Kalsum U, et al. Farmakologi Dasar. Malang: UB Press; 2017. 139-140 p.

Kizior R, Hodgson B. Saunders Nursing Drug Handbook. USA: Elsevier Ltd; 2016.141 p

Hatauruk JA, Siregar SB. Kataeak: 101 Jawaban atas Pertanyaan anda. Jakarta: Gramedia; 2017

Rathi SK, Dsouza P. Rational and Ethical Use Of Topical Cortcosteroid Based on Safety and Eficacy. Indian J Dermato. 2012; 57(4):251-9

Topical Steroids Potency Ranking Table (hihjs to lowest). Available From: http//www/dermnetnz.org/treatments/topical-Steroids.html.

Valencia IC, Kerdel FA. Topical Corticosteroids, In: Wolff K, Goldsmith, LA, Katz SI, Gilcherst BA, Paller AS, Leffel DJ, eds. Fitzpatrick’s Dermatology in General Medicine 8th ed. New York McGraw-Hill Co Inc; 2012.p. 2650-65

Johan Reshiani.2015. Penggunaan Kortikosteroid Topikal yang Tepat. Jurnal Cermin dunia Kedokteran. Vol 42 Hal 227-230. Jawabarat. Cimahi

Elfreda SS. Putu Ristyaning AS. Rani Himayani. 2023. Pengaruh Penggunaan Obat Kortikosteroid, Terhadap kejadian Glaukoma Akut. Medula. Vol 13. Nomor 4.1. Juni 2023 Hal 144-149

Lam Cs, Umi Kalthum MN, Norshamsiah MD, Bastion M. Case series of Children With Steroid-Induced Galucoma. Malays Fam Physician.2018. 13 (3):32-7.

Andole S, Senthil S. Ocular Surface Disease And Anti-Glaucoma Medications: Various Features, Diagnosis, And Management Guidelines. Semin Ophthalmol.2022. Vol.1: 1-9

Chang CJ, Somohano k, Zemsky C, Uhlemann AC, Liebmann J, Cioffi GA, Al Aswad LA, Lynch SV, Winn BJ. Topical Galucoma Therapy Is Associated With Alterations Of The Ocular Surface Microbiome. Invest OphThalmol Vis Sci. 2022.63 (9):32

Shroff S, Thomas RK, D'Souza G, Nithyanandan S. The effect of inhaled steroids on the intraocular pressure. Digit J Ophthalmol. 2018. 24(3):6-9.

Csorba A, Soproni A, Maneschg O, Nagy ZZ, Szamosi A. Application of corticosteroid eye drops for allergic eye diseases in children. Orv Hetil. 2019. 160(9):329-37.

Artini W. Steroid-Induced Glaucoma. FKUI;2012

Phulke S. Kaushik S, Kaur S, Pandav SS. Steroid-induced Glaucoma: An Avoidable Irreversible Blindness. J Curr Glaucoma Pract. 2017;11(2);67-72

Zhang, G. et al. (2018) ‘The role of Dexamethasone in clinical pharmaceutical treatment for patients with cataract surgery’, pp. 2177–2181. doi: 10.3892/etm.2017.5639.

Eka, S. et al. (2012) ‘Karakteristik penderita katarak senilis yang dilakukan tindakan pembedahan katarak di RSUP H . Adam Malik Medan tahun 2012’, 45(3), pp. 149–153.

Zhang, G. et al. (2018) ‘The role of Dexamethasone in clinical pharmaceutical treatment for patients with cataract surgery’, pp. 2177–2181. doi: 10.3892/etm.2017.5639

Husna I. Dkk. (2019). Evaluasi Efek Samping Penggunaan Obat Tetes Mata

Kortikosteroid Pada Pasien Pasca Operasi Di Instalasi Farmasi Rumah Sakit Mata Jakarta Eye Center Kedoya, Archives Pharmacia vol 1 nomor 2.